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Research Grants

AICR has contributed more than $95 million for innovative research conducted at universities, hospitals and research centers across the country.

2010 Funded Research Grants

Download a PDF of Currently Funded Research Grants

Grants: Adolescent diet and breast cancer (2009)
A. Lindsay Frazier, MD, ScM is studying the link between adolescent lifestyle and breast cancer risk later in life by tracking the diets and activity levels over 9000 girls aged 9-17.

Grants: Lifestyle and dietary factors during adolescence and risk of colorectal adenoma (2009)
Kana Wu, MD, MPH is analyzing the link between adolescent diets and colorectal cancer risk later in life among a large group of adult women.

Grants: Vitamin B6 and colorectal neoplasia: modification by time (2009)
Jung Eun Lee, ScD is examining how the intake of vitamin B6 influences colon cancer at various stages of the cancer process.

Grants: Dietary factors in relation to prostate cancer risk and survival (2009)
Julie Kasperzyk, ScD is examining the effect of dietary factors like dairy foods and fish on prostate cancer risk among men in three large, ongoing studies.

Grants: Chemoprevention of DSS-induced colitis and colorectal cancer by dietary vitamin D in mice with defective TGFbeta's
Lillian Maggio-Price, PhD, VMD is examining how vitamin D helps to regulate genes that keep colon cells healthy and cancer-free.

Grants: Therapeutic synergy between piperine and docetaxel against prostate cancer (2009)
Robert Uzzo, MD is using piperine, a pungent substance found in black peppers, to increase the effectiveness of a widely used prostate cancer chemotherapy.

Grants: The role of dietary fiber and gut microflora in prevention of colorectal cancer (2009)
Scott Bultman, PhD received an AICR grant to study how the natural bacteria that live in our guts help protect us against colon cancer.

Grants: The role of caffeine in breast tumor metastasis to the brain (2009)
Ania Majewska, PhD is testing a hypothesis that caffeine's stimulative effect on neurons may play a protective role in keeping breast cancer from metastasizing (spreading) to the brain.

Grants: The alpha tocopherol transfer protein, vitamin E, and prostate cancer (2009)
Samantha Morley, PhD is testing whether vitamin E can make prostate cancer cells more sensitive to treatment.

Grants: Metabolic inflexibility: a potential link between obesity and postmenopausal breast cancer (2009)
Erin Giles, PhD is studying how weight gain that coincides with menopause increases risk for postmenopausal breast cancer.

Grants: Dietary choline and betaine, related genetic polymorphisms, and the risk of colorectal cancer (2009)
Unhee Lim, PhD is studying the intake of two nutrients among a large multiethnic population to determine if genetic factors play a role in the susceptibility to cancers that are linked to nutrient deficiencies.

Grants: Factors determining the apoptotic response of colorectal carcinoma cells to butyrate (2009)
Michael Bordonaro, PhD is studying a specific cell-signaling pathway that may explain why fiber-rich diets protect against colon cancer in some people, but not in others.

Grants: Does vitamin D status modulate colon cancer driven by APC allele loss? (2009)
James Fleet, PhD is using his AICR grant to test how a wide range of vitamin D levels influence risk for colon cancer.

Grants: Targeting cFLIP by lupeol, a dietary triterpene, for chemoprevention of pancreatic cancer (2009)
Mohammad Saleem Bhat, PhD is determining the ability of a compound called lupeol, found in figs, mangoes, olives, strawberries and grapes, to make pancreatic cancer cells more responsive to chemotherapy.

Grants: Dietary induced sporadic colon cancer (2009)
Leonard Augenlicht, PhD is using his AICR grant to examine how and why various aspects of "Western" diets alter the lining of the colon in ways that make colon cancer more likely.

Grants: Enhancement of doxorubicin therapy via protecting against chronic heart failure by a unique nutraceutical (2009)
Yunbo Li, MD, PhD is testing whether a substance found in cruciferous plants can make a common chemotherapy drug less damaging to the hearts of cancer patients.

Grants: Genetic interactions in vitamin D levels and colorectal cancer in African Americans (2009)
Nathan Ellis, PhD is investigating whether the higher rate of colorectal cancers among African-Americans may be due in part to genetic factors that influence their bodies' production of vitamin D.

Grants: The effects of dietary selenium supplementation on breast cancer metastasis (2009)
Andrea Mastro, PhD's AICR grant involves the mineral selenium and its effect on breast cancer's ability to spread to the rest of the body.

Grants: Effect of EGCG, a phytochemical from green tea, on integrin activation and cancer cell metastasis (2009)
Chungho Kim, PhD is studying a compound found in green tea for its ability to interfere with a process cancer cells use to spread to other parts of the body.

Grants:The effect of a lycopene-rich tomato extract on gene expression in benign prostate tissue (2009)
Peter Gann, MD, ScD is conducting a randomized trial to determine how lycopene, a tomato component noted for its anti-cancer activity, influences healthy prostate tissue in ways that make cancer less likely.

Grants: Soy sphingadienes and related compounds in colon cancer chemoprevention and treatment (2009)
Julie Saba, MD, PhD is studying the ability of substances found in soy to kill colon cancer cells without damaging healthy cells.

Grants: Role of oxGPCs/PAFR in BITC mediated suppression of melanoma (2009)
Ravi Sahu, PhD's work involves a component of cruciferous vegetables that has shown the ability to stop the growth of pancreatic cancer.

Grants: Interactive effect of flaxseed and trastuzumab in reducing the growth of human breast tumors over expressing HER2 (2009)
Lilian Thompson, PhD is studying whether pairing a common chemotherapy drug with dietary intake of flaxseed may make the drug more effective and less toxic.

Grants: Calorie restriction, lipid peroxidation, and mammary tumor prevention (2009)
Christine Seppanen, PhD is using her AICR grant to study intermittent caloric restriction as a means to reduce breast cancer risk.

Grants: Regulation of the MYCN oncogene in neuroblastoma (2009)
Randal Wada, MD is using an AICR grant to study the effect of a form of vitamin A on a series of genes that can cause the childhood cancer called neuroblastoma to become benign.

Grants: Does dietary folate intake modify treatment-related toxicity or disease outcome among children with acute lymphob (2009)
Kara Kelly, MD's AICR grant investigates dietary means to make a widely used chemotherapy for the childhood cancer called acute lymphoblastic leukemia (ALL) more effective.

Grants: Epigenetics of genistein and/or soy isoflavone in breast cancer prevention (2009)
Yuanyuan Li, MD, PhD is using an AICR grant to study how the soy component genistein affects the functioning of various genes associated with breast cancer.

Grants: Effects of essential amino acid intake on net protein synthesis in weight-losing non-small cell lung cancer patie (2009)
MariŽlle Engelen, PhD is studying if an essential amino acid can help prevent the life-threatening weight loss experienced by some lung cancer patients.

Grants: Prevention of tamoxifen resistance by green tea polyphenols (2009)
Harini Aiyer, PhD is studying polyphenols found in green tea to determine if they can help prevent the resistance to tamoxifen that many breast cancer patients experience.

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